A man has been gored in the Pamplona bull run as one of the animals ran close to the side of the street, pinning runners to the wall.
Another five people were injured, officials in the northern Spanish city said.
The man was gored in his left leg during the sixth run of the 2019 San Fermin festival on Friday, while another person had a badly bruised chest.
Several bulls and dozens of runners slipped and fell during the latest dash along cobbled streets to Pamplona’s bullring.
Another four people – two Americans and two Spaniards – had already been gored since the festival began with daily races on Sunday.
The event’s origin is based on the historical need to move the bulls from fields outside the city, where they were bred, to the bullring, where they would be killed in the evening.
Young people would jump between them to show off their bravado.
The animals are the ones that feature in an afternoon bullfight.
Protesters have complained that new safety measures, including the application of a non-slip chemical along the route, have made the run too safe and taken some of the buzz away.
Dozens of participants staged a sit-down protest, claiming that measures to train the steers (neutered bulls) which lead the bulls along the route had sanitised the event.
“The steers are over-trained,” said Alberto Buitrago, who has been taking part since 2002. “They block off the bulls via an arrow formation and keep the bulls away from the runners. We’re losing all the essence of the bull run.”
On Thursday, one person was badly gored in the forearm. The Red Cross said 67 people were treated, seven of them in hospital, after that day’s running of the bulls.
Before the festival began, there was a protest from animal rights activists who claim that not many of the million or so people who travel to Pamplona each year know that the bulls die after the daily runs.